LrgpV1, Main, Exploration, bibRecord, 000C09

Lipase-catalyzed synthesis of hydrophobically modified dextrans: Activity and regioselectivity of lipase from Candida rugosa

Identifieur interne : 000C09 ( Main/Exploration ); précédent : 000C08; suivant : 000C10

Lipase-catalyzed synthesis of hydrophobically modified dextrans: Activity and regioselectivity of lipase from Candida rugosa

Auteurs : Kultida Kaewprapan [Thaïlande] ; Jirarut Wongkongkatep [Thaïlande] ; Watanalai Panbangred [Thaïlande] ; Pranee Phinyocheep [Thaïlande] ; Emmanuelle Marie [France] ; Alain Durand [France] ; Pranee Inprakhon [Thaïlande]

Source :

Journal of bioscience and bioengineering [ 1389-1723 ] ; 2011.

RBID : Pascal:11-0419313

Descripteurs français

Pascal (Inist)
- Triacylglycerol lipase, Catalyse, Dextran, Régiosélectivité, Candida rugosa, Vecteur médicament, Transestérification, Ester.

English descriptors

KwdEn :
- Candida rugosa, Catalysis, Dextran, Drug carrier, Ester, Regioselectivity, Transesterification, Triacylglycerol lipase.

Abstract

Vinyl decanoate-modified dextran macromolecules (DexT40-VD) were synthesized in dimethyl sulfoxide at 50°C using lipase AY from Candida rugosa for catalyzing transesterification between polysaccharide and vinyl fatty esters. The extent of dextran modification (quantified by the molar ratio of attached alkyl tails to sugar repeat units) with native-, pH-adjusted-, 18-crown-6 ether pretreated pH-adjusted-, and stepwise addition of pretreated lipase AY yielded <3%, 49%, 64% and 96% modified dextran respectively. Lipase AY accelerated the transesterification of DexT40 from 2- to 63-fold higher than the non-catalyzed system. This procedure was extended to other acyl donors showing that modification pattern exhibited regioselectivity depending on acyl donor structure. Regioselectivity equaled between 2- and 3-OH with saturated fatty acyl donors. The 2-OH was favored for unsaturated fatty acyl donors, while sterically hindered acyl donors oriented modification toward 3-OH position. DexT40-VD at 96% modification was a water-insoluble polymer forming 150 nm diameter nanoparticles in water which can be used as drug carrier systems.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000181
to stream PascalFrancis, to step Curation: 000930
to stream PascalFrancis, to step Checkpoint: 000180
to stream Main, to step Merge: 000D37
to stream Main, to step Curation: 000C09

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Lipase-catalyzed synthesis of hydrophobically modified dextrans: Activity and regioselectivity of lipase from Candida rugosa</title>
<author><name sortKey="Kaewprapan, Kultida" sort="Kaewprapan, Kultida" uniqKey="Kaewprapan K" first="Kultida" last="Kaewprapan">Kultida Kaewprapan</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biotechnology, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</s1>
<s2>Bangkok</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wongkongkatep, Jirarut" sort="Wongkongkatep, Jirarut" uniqKey="Wongkongkatep J" first="Jirarut" last="Wongkongkatep">Jirarut Wongkongkatep</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biotechnology, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</s1>
<s2>Bangkok</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Panbangred, Watanalai" sort="Panbangred, Watanalai" uniqKey="Panbangred W" first="Watanalai" last="Panbangred">Watanalai Panbangred</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biotechnology, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</s1>
<s2>Bangkok</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>MU-OU-CRC center, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Phinyocheep, Pranee" sort="Phinyocheep, Pranee" uniqKey="Phinyocheep P" first="Pranee" last="Phinyocheep">Pranee Phinyocheep</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Marie, Emmanuelle" sort="Marie, Emmanuelle" uniqKey="Marie E" first="Emmanuelle" last="Marie">Emmanuelle Marie</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Laboratoire de Chimie-Physique Macromoléculaire, UMR 7568 CNRS-Nancy University, ENSIC, BP20451</s1>
<s2>54001 Nancy</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Grand Est</region>
<region type="old region" nuts="2">Lorraine (région)</region>
<settlement type="city">Nancy</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Durand, Alain" sort="Durand, Alain" uniqKey="Durand A" first="Alain" last="Durand">Alain Durand</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Laboratoire de Chimie-Physique Macromoléculaire, UMR 7568 CNRS-Nancy University, ENSIC, BP20451</s1>
<s2>54001 Nancy</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Grand Est</region>
<region type="old region" nuts="2">Lorraine (région)</region>
<settlement type="city">Nancy</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Inprakhon, Pranee" sort="Inprakhon, Pranee" uniqKey="Inprakhon P" first="Pranee" last="Inprakhon">Pranee Inprakhon</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biotechnology, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</s1>
<s2>Bangkok</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">11-0419313</idno>
<date when="2011">2011</date>
<idno type="stanalyst">PASCAL 11-0419313 INIST</idno>
<idno type="RBID">Pascal:11-0419313</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000181</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000930</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000180</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000180</idno>
<idno type="wicri:doubleKey">1389-1723:2011:Kaewprapan K:lipase:catalyzed:synthesis</idno>
<idno type="wicri:Area/Main/Merge">000D37</idno>
<idno type="wicri:Area/Main/Curation">000C09</idno>
<idno type="wicri:Area/Main/Exploration">000C09</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Lipase-catalyzed synthesis of hydrophobically modified dextrans: Activity and regioselectivity of lipase from Candida rugosa</title>
<author><name sortKey="Kaewprapan, Kultida" sort="Kaewprapan, Kultida" uniqKey="Kaewprapan K" first="Kultida" last="Kaewprapan">Kultida Kaewprapan</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biotechnology, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</s1>
<s2>Bangkok</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wongkongkatep, Jirarut" sort="Wongkongkatep, Jirarut" uniqKey="Wongkongkatep J" first="Jirarut" last="Wongkongkatep">Jirarut Wongkongkatep</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biotechnology, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</s1>
<s2>Bangkok</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Panbangred, Watanalai" sort="Panbangred, Watanalai" uniqKey="Panbangred W" first="Watanalai" last="Panbangred">Watanalai Panbangred</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biotechnology, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</s1>
<s2>Bangkok</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>MU-OU-CRC center, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Phinyocheep, Pranee" sort="Phinyocheep, Pranee" uniqKey="Phinyocheep P" first="Pranee" last="Phinyocheep">Pranee Phinyocheep</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Marie, Emmanuelle" sort="Marie, Emmanuelle" uniqKey="Marie E" first="Emmanuelle" last="Marie">Emmanuelle Marie</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Laboratoire de Chimie-Physique Macromoléculaire, UMR 7568 CNRS-Nancy University, ENSIC, BP20451</s1>
<s2>54001 Nancy</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Grand Est</region>
<region type="old region" nuts="2">Lorraine (région)</region>
<settlement type="city">Nancy</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Durand, Alain" sort="Durand, Alain" uniqKey="Durand A" first="Alain" last="Durand">Alain Durand</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Laboratoire de Chimie-Physique Macromoléculaire, UMR 7568 CNRS-Nancy University, ENSIC, BP20451</s1>
<s2>54001 Nancy</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Grand Est</region>
<region type="old region" nuts="2">Lorraine (région)</region>
<settlement type="city">Nancy</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Inprakhon, Pranee" sort="Inprakhon, Pranee" uniqKey="Inprakhon P" first="Pranee" last="Inprakhon">Pranee Inprakhon</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biotechnology, Faculty of Science, Mahidol University, Rama 6 Road</s1>
<s2>Bangkok 10400</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Bangkok 10400</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</s1>
<s2>Bangkok</s2>
<s3>THA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Thaïlande</country>
<wicri:noRegion>Center of Excellence on Agricultural Biotechnology: (AG-BIO / PERDO-CHE)</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of bioscience and bioengineering</title>
<title level="j" type="abbreviated">J. biosci. bioeng.</title>
<idno type="ISSN">1389-1723</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of bioscience and bioengineering</title>
<title level="j" type="abbreviated">J. biosci. bioeng.</title>
<idno type="ISSN">1389-1723</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Candida rugosa</term>
<term>Catalysis</term>
<term>Dextran</term>
<term>Drug carrier</term>
<term>Ester</term>
<term>Regioselectivity</term>
<term>Transesterification</term>
<term>Triacylglycerol lipase</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Triacylglycerol lipase</term>
<term>Catalyse</term>
<term>Dextran</term>
<term>Régiosélectivité</term>
<term>Candida rugosa</term>
<term>Vecteur médicament</term>
<term>Transestérification</term>
<term>Ester</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Vinyl decanoate-modified dextran macromolecules (DexT40-VD) were synthesized in dimethyl sulfoxide at 50°C using lipase AY from Candida rugosa for catalyzing transesterification between polysaccharide and vinyl fatty esters. The extent of dextran modification (quantified by the molar ratio of attached alkyl tails to sugar repeat units) with native-, pH-adjusted-, 18-crown-6 ether pretreated pH-adjusted-, and stepwise addition of pretreated lipase AY yielded <3%, 49%, 64% and 96% modified dextran respectively. Lipase AY accelerated the transesterification of DexT40 from 2- to 63-fold higher than the non-catalyzed system. This procedure was extended to other acyl donors showing that modification pattern exhibited regioselectivity depending on acyl donor structure. Regioselectivity equaled between 2- and 3-OH with saturated fatty acyl donors. The 2-OH was favored for unsaturated fatty acyl donors, while sterically hindered acyl donors oriented modification toward 3-OH position. DexT40-VD at 96% modification was a water-insoluble polymer forming 150 nm diameter nanoparticles in water which can be used as drug carrier systems.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
<li>Thaïlande</li>
</country>
<region><li>Grand Est</li>
<li>Lorraine (région)</li>
</region>
<settlement><li>Nancy</li>
</settlement>
</list>
<tree><country name="Thaïlande"><noRegion><name sortKey="Kaewprapan, Kultida" sort="Kaewprapan, Kultida" uniqKey="Kaewprapan K" first="Kultida" last="Kaewprapan">Kultida Kaewprapan</name>
</noRegion>
<name sortKey="Inprakhon, Pranee" sort="Inprakhon, Pranee" uniqKey="Inprakhon P" first="Pranee" last="Inprakhon">Pranee Inprakhon</name>
<name sortKey="Inprakhon, Pranee" sort="Inprakhon, Pranee" uniqKey="Inprakhon P" first="Pranee" last="Inprakhon">Pranee Inprakhon</name>
<name sortKey="Kaewprapan, Kultida" sort="Kaewprapan, Kultida" uniqKey="Kaewprapan K" first="Kultida" last="Kaewprapan">Kultida Kaewprapan</name>
<name sortKey="Panbangred, Watanalai" sort="Panbangred, Watanalai" uniqKey="Panbangred W" first="Watanalai" last="Panbangred">Watanalai Panbangred</name>
<name sortKey="Panbangred, Watanalai" sort="Panbangred, Watanalai" uniqKey="Panbangred W" first="Watanalai" last="Panbangred">Watanalai Panbangred</name>
<name sortKey="Panbangred, Watanalai" sort="Panbangred, Watanalai" uniqKey="Panbangred W" first="Watanalai" last="Panbangred">Watanalai Panbangred</name>
<name sortKey="Phinyocheep, Pranee" sort="Phinyocheep, Pranee" uniqKey="Phinyocheep P" first="Pranee" last="Phinyocheep">Pranee Phinyocheep</name>
<name sortKey="Wongkongkatep, Jirarut" sort="Wongkongkatep, Jirarut" uniqKey="Wongkongkatep J" first="Jirarut" last="Wongkongkatep">Jirarut Wongkongkatep</name>
<name sortKey="Wongkongkatep, Jirarut" sort="Wongkongkatep, Jirarut" uniqKey="Wongkongkatep J" first="Jirarut" last="Wongkongkatep">Jirarut Wongkongkatep</name>
</country>
<country name="France"><region name="Grand Est"><name sortKey="Marie, Emmanuelle" sort="Marie, Emmanuelle" uniqKey="Marie E" first="Emmanuelle" last="Marie">Emmanuelle Marie</name>
</region>
<name sortKey="Durand, Alain" sort="Durand, Alain" uniqKey="Durand A" first="Alain" last="Durand">Alain Durand</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Lorraine/explor/LrgpV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C09 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000C09 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Lorraine
   |area=    LrgpV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:11-0419313
   |texte=   Lipase-catalyzed synthesis of hydrophobically modified dextrans: Activity and regioselectivity of lipase from Candida rugosa
}}

This area was generated with Dilib version V0.6.32.
Data generation: Sat Nov 11 15:47:48 2017. Site generation: Wed Mar 6 23:31:34 2024

	Serveur d'exploration sur le LRGP
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le LRGP

Lipase-catalyzed synthesis of hydrophobically modified dextrans: Activity and regioselectivity of lipase from Candida rugosa

Lipase-catalyzed synthesis of hydrophobically modified dextrans: Activity and regioselectivity of lipase from Candida rugosa

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri